An increase in the number of cells takes place during growth and when one of these cells finishes its physiological function or detects DNA or cell damage, it undergoes a physiological process known as apoptosis that induces its own death. Cell proliferation is tightly controlled, according to the organism needs. In metazoans, somatic cells divide normally during the process known as mitosis. Life and death are essential parts of the natural cycle of all multicellular organisms. Unidad de Investigación, Hospital General Universitario de Elche, Elche (Alicante), Spainġ.1.Unidad AECC de Investigación Traslacional en Cáncer, Hospital Universitario Virgen de la Arrixaca, Instituto Murciano de Investigación Biosanitaria, Murcia, Spain.Centro Nacional de Investigaciones Cardiovasculares, Departamento de Desarrollo y Reparación Cardiovascular, Madrid, Spain.Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche (Alicante), Spain.
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